Defining Novel Pathway to Lipodystrophy
نویسندگان
چکیده
منابع مشابه
Novel Forms of Lipodystrophy
L ipodystrophies are a heterogeneous group of conditions in which individuals never develop or progressively lose adipose tissue in parts or all of their bodies (1,2) (Table 1). In this commentary, we will make the case that 1) defining lipodystrophy is a work in progress; 2) not all forms of lipodystrophy are very rare; 3) lipodystrophy and obesity can occur simultaneously and their metabolic ...
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Lipodystrophic syndromes encompass a heterogeneous group of rare disorders characterized by partial or generalized loss of adipose tissue depots (1). They are commonly associated with dyslipidemia, hepatic steatosis, and severe insulin resistance (2). The fact that insulin resistance and the consequent progression to diabetes can result from either obesity or lipodystrophy reflects the crucial ...
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Recently new evidence about fibroblast growth factor 21 (FGF21) highlights the opportunities to use this molecule in new pharmaceutical formulations to combat type 2 diabetes and metabolic syndrome. It is well known that HIV is per se a condition of insulin resistance and in particular the patient with HIV-related lipodystrophy has a condition strictly related to metabolic syndrome. Lipodystrop...
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ژورنال
عنوان ژورنال: Canadian Journal of Diabetes
سال: 2013
ISSN: 1499-2671
DOI: 10.1016/j.jcjd.2013.08.197